Cutaneous Alternariosis Caused by Alternaria infectoria: Three Cases in Kidney Transplant Patients

Phaeohyphomycosis caused by Alternaria infectoria presenting as multiple vegetating lesions in a renal transplant patient.

The genus Alternaria is one of the most common black moulds and appears to be increasing as a causative agent of subcutaneous phaeohyphomycosis, particularly among immunosuppressed patients. A 53-year-old patient who had received a kidney transplant presented with multiple verrucous lesions on the distal extremities. Positive histopathology and cultures, in addition to rDNA ITS region sequencin...

Sporotrichoid phaeohyphomycosis due to Alternaria infectoria.

We describe a cardiac transplant patient who had human cutaneous alternariosis with a sporotrichoid distribution of skin lesions. In this patient identification of the causative organism Alternaria infectoria was achieved by sequencing the rDNA internal transcribed spacer domain. Treatment with itraconazole led to clinical resolution within 4 months.

Cutaneous alternariosis.

Alternariosis is a fungal infection usually described in immunodeficient patients. We report a case of cutaneous alternariosis in a renal transplant recipient caused by Alternaria alternata. The patient was treated with intralesional amphothericin B and surgical excision of one non-responding lesion was performed.

Success of posaconazole therapy in a heart transplanted patient with Alternaria infectoria cutaneous infection.

Cutaneous Alternaria spp. infections occur mainly in immunosuppressed patients and itraconazole is considered as the drug of choice. We report the case of a 64-year-old heart transplanted female patient with multiple cutaneous lesions caused by Alternaria infectoria. Treatment with posaconazole resulted in complete recovery. Due to lower minimal inhibitory concentrations, better distribution an...

Relapse of cutaneous alternaria infectoria in a renal transplant recipient after 2 years.